Clinical Care Options: "Importance of Pharmacokinetics and Adherence to Avoid Emergence of Resistant HCV Variants"

A new CCO module is available here, focusing on the importance of PK and compliance to regimens in an effort to stem HCV resistance. The parallels between HCV antivirals and the evolution of HIV antiretrovirals are becoming numerous. Pharmacokinetics, pharmacogenetics and pharmacodynamics will all increase in importance as HCV drug development marketplace continues to move forward and potentially become as competitive as the HIV marketplace was back in the mid-90's and 2000's.