Clinical Care Options: "Importance of Pharmacokinetics and Adherence to Avoid Emergence of Resistant HCV Variants"

A new CCO module is available here, focusing on the importance of PK and compliance to regimens in an effort to stem HCV resistance. The parallels between HCV antivirals and the evolution of HIV antiretrovirals are becoming numerous. Pharmacokinetics, pharmacogenetics and pharmacodynamics will all increase in importance as HCV drug development marketplace continues to move forward and potentially become as competitive as the HIV marketplace was back in the mid-90's and 2000's.

Clinical Care Options inPractice now offering free online Hepatology textbook...

Clinical Care Options inPractice now offering free online Hepatology textbook....
CCO's inPractice now offering a new Hepatology medical textbook to complement their companion texts in Oncology and HIV. It's free and updated on a regular basis. It's search function allows you to browse for answers at the point of care. It can be found here: http://www.clinicaloptions.com/inPractice.aspx

Some of the texts include:

Virology and Immunology of Hepatitis Viruses
Hepatitis A and E
Hepatitis B Epidemiology, Pathogenesis, Diagnosis, and Natural History
Management of Hepatitis B Infection
Hepatitis B Management in Special Populations
Hepatitis Delta Virus
Hepatitis C Virus Epidemiology, Pathogenesis, Diagnosis, and Natural History
Management of Hepatitis C Infection
Hepatitis C Management in Special Populations
Other Viruses That Affect the Liver

HCV Resistance: Similarities and Differences With HIV CME on Clinical Care Options

A great new CME with Stuart Ray, MD from Johns Hopkins University reviewing the similarities and differences in HCV resistance compared to HIV. Highly recommended. Free, but registration to Clinical Care Options required. Link here

New CCO Interactive and Downloadable Slide Set Available: Future Generations: Understanding the Similarities and Differences Among Direct-Acting Antivirals for Hepatitis C

For those that like to geek-out to quality slide decks (the hallmark of the folks at CCO) there is both an interactive presentation (with Stefan Zeuzem, MD) and a downloadable slide deck entitled "Future Generations: Understanding the Similarities and Differences Among Direct-Acting Antivirals for Hepatitis C". This happens to come at a perfect time for the DAA layperson, right before the impending launch of the first generation DAAs, Telaprevir and Boceprevir. You can watch and/or download the presentation right here